Elsa Peretti, who went from Halston model and Studio 54 regular in the 1960s and ’70s to one of the world’s most famous jewelry designers with timeless, fluid Tiffany & Co. collections often inspired by nature, has died. She was 80.

She died Thursday night in her sleep at home in a small village outside Barcelona, Spain, according to a statement from her family office in Zurich and the Nando and Elsa Peretti Foundation.

Peretti’s sculptural cuff bracelets, bean designs and open-heart pendants are among her most recognizable work. She lent her classical aesthetic to functional goods, too, including bowls,